Marcella Chiari leads the Analytical Microsystem group at the Institute of Chemistry of Molecular Recognition (ICRM), one of the institutes of the National Research Council of Italy. ICRM activities cover the following areas: 1) Biomolecules (natural bioactive substances and synthesis of compounds of biological interest); 2) Chemical biotechnologies (bioconversions, enzyme technology and analytical methodologies); 3) Mechanisms of bioregulation (molecular basis of biological regulation and experimental and theoretical studies of molecular recognition). Dr. Chiari's team develops micro analytical techniques for genomics and proteomics. She is active in different projects, organized around the following themes: 1) automated systems for the analysis of gene and protein expression, 2) miniaturized analytical systems for microchip electrophoresis, 3) chemical aspects of microarray technology. She has an internationally recognized know-how in the production of polymeric coatings for microchip electrophoresis and microarray on different materials including glass, silicon oxide, polydimethylsiloxane, polyethylene and gold. The team, comprising organic, bioorganic and computational chemists, biochemists and biotechnologists, carries out researches on the various aspects of the microarray technology, from surface modification trough polymer coating, to development of clinically relevant bioassays. The interdisciplinary characteristics of the group ensure an incisive work of development of innovative analytical methodologies in the micro-scale for the study of DNA and proteins, for diagnostics applications. Dr. Chiari coordinates the EU, H2020-FETOPEN-2016-2017 project INDEX, Integrated nanoparticle isolation and detection system for complete on-chip analysis of exosomes. The targeted scientific breakthroughs of project INDEX is the integration of the technologies towards the first complete system to reduce the isolation and analysis time of EVs in human diagnostics. Author of more than 220 publications in International peer reviewed journals and more than 10 international patents, Dr. Chiari is cofounder of the companies Lucidant Polymers, LLC Sunnyvale, CA 94089 and Life Line Lab S.r.l. Guidonia, Rome, Italy.